Ccl4 3d Model. There are many ways to induce nafld nash for preclinical rodent modeling methods include dietary manipulation employing high fat high cholesterol high fructose methionine choline deficient diets or combinations of the above chemotoxic agent induction and acute liver injury models. The carbon tetrachloride ccl4 induced mouse model has been historically relied upon to study liver injury and regeneration.
A quick explanation of the molecular geometry of ccl4 including a description of the ccl4 bond angles looking at the ccl4 lewis structure we can see that the. Ccl4 treatment in mice causes significant fibrosis within a relatively short treatment period and it is still occasionally utilised for testing drugs that target the fibrotic aspect of nash. Nash induction with ccl 4.
A ccl4 lewis structure is a diagram that represents the electron configuration of covalently bonded compounds lewis structures are meant to provide a visualization of the atomic structure and the distribution of electrons in a given chemical compound.
Carbon tetrachloride ccl4 cid 5943 structure chemical names physical and chemical properties classification patents literature biological activities. Carbon tetrachloride ccl4 cid 5943 structure chemical names physical and chemical properties classification patents literature biological activities. Ccl4 treatment in mice causes significant fibrosis within a relatively short treatment period and it is still occasionally utilised for testing drugs that target the fibrotic aspect of nash. It has practically no flammability at lower temperatures.
